Perlane® is the latest dermal filler used to replace volume and restore youthful contours to the skin to smooth away moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth. Like Restylane®, Perlane® is a hyaluronic acid made in the same biotechnical process. The difference is in the gel particle size. Perlane® gel particles are larger and designed for deeper injection than Restylane. Your doctor will decide which is best for you. To learn more or request information by email, click below.